Disease: Arthralgia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
VDR P11473 vitamin D receptor Nuclear receptor 1.7E-05 0.352 0.885
TNFRSF11B O00300 TNF receptor superfamily member 11b 0.16 0.422 0.808
TNFRSF11A Q9Y6Q6 TNF receptor superfamily member 11a 8.8E-03 0.480 0.846
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885
SLC40A1 Q9NP59 solute carrier family 40 member 1 Transporter 0.99 0.570 0.731
PTPN22 Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 3.5E-21 0.438 0.846
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
PRTN3 P24158 proteinase 3 Enzyme 3.8E-05 0.503 0.808
PRDX2 P32119 peroxiredoxin 2 Enzyme 8.7E-02 0.474 0.885
PHEX P78562 phosphate regulating endopeptidase homolog X-linked Enzyme 1.00 0.548 0.808
PADI4 Q9UM07 peptidyl arginine deiminase 4 4.6E-16 0.494 0.808
NOD2 Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 2.0E-30 0.423 0.923
NFKB2 Q00653 nuclear factor kappa B subunit 2 Transcription factor 1.00 0.509 0.808
MTCO2P12 MT-CO2 pseudogene 12 0.368 0.962
MMP8 P22894 matrix metallopeptidase 8 Enzyme 1.1E-24 0.488 0.808
MMP3 P08254 matrix metallopeptidase 3 Enzyme 5.7E-15 0.408 0.885
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
IRF5 Q13568 interferon regulatory factor 5 Transcription factor 9.0E-03 0.489 0.731
IRAK1 P51617 interleukin 1 receptor associated kinase 1 Kinase 0.99 0.506 0.808
IL6 P05231 interleukin 6 0.32 0.248 0.962